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Research Updates

Latest peer-reviewed publications on longevity compounds, peptides, and biohacking science — pulled directly from PubMed in real time.

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Latest Publications

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NMN (Nicotinamide Mononucleotide)2026PubMed
New mechanistic insight into SARM1 activation: TRIM32-mediated ubiquitination is a key lever that actuates SARM1's catalytic action, leading to axon degeneration and cell death.

Murata H, Tomonobu N, Yamamoto KI et al.·Frontiers in neural circuits

NMN (Nicotinamide Mononucleotide)2026PubMed
A minimal three-arm oral regimen for healthspan: mechanistic alignment with transcriptomic signals from a large parental-lifespan GWAS.

Cheung N·Frontiers in aging

NMN (Nicotinamide Mononucleotide)2026PubMed
A Staged Translational Framework for Evaluating Oral Glutamatergic and Senescence-Modulating Strategies in Treatment-Resistant Depression.

Cheung N·Drug design, development and therapy

BPC-157 (Body Protection Compound)Jun 2026PubMed
Stable pentadecapeptide therapy counteracts gentamicin-induced nephrotoxicity via nitric oxide-system modulation: evidence from a triple nitric oxide-agent approach in rats.

Vukoja I, Vlainic J, Francina M et al.·Journal of physiology and pharmacology : an official journal of the Polish Physiological Society

BPC-157 (Body Protection Compound)May 2026PubMed
Unilateral Adrenalectomy, and the Stable Pentadecapeptide BPC 157 as Therapy in Rats-A Cytoprotection Approach.

Smoday IM, Vukovic V, Oroz K et al.·Pharmaceuticals (Basel, Switzerland)

BPC-157 (Body Protection Compound)May 2026PubMed
BPC-157 and Its Novel Hybrid Analogs as Inhibitors of Acetylcholinesterase.

Jelińska J, Józwiak M, Szeleszczuk Ł et al.·International journal of molecular sciences

Epithalon (Epitalon)Mar 2025PubMed
Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties.

Araj SK, Brzezik J, Mądra-Gackowska K et al.·International journal of molecular sciences

Epithalon (Epitalon)May 2004PubMed
Peptide promotes overcoming of the division limit in human somatic cell.

Khavinson VKh, Bondarev IE, Butyugov AA et al.·Bulletin of experimental biology and medicine

Epithalon (Epitalon)Sep 2003PubMed
Effect of regulatory peptides on gene transcription.

Khavinson VKh, Shataeva LK, Chernova AA·Bulletin of experimental biology and medicine

Berberine (Liposomal)Aug 2026PubMed
[Research progress on traditional Chinese medicine in prevention and treatment of metabolic diseases via SIRT1/AMPK signaling pathway].

Hu JP, Zhang S, Yan LJ et al.·Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

Berberine (Liposomal)Aug 2026PubMed
Metabolic and Anti-Inflammatory Effects of Berberine-Rationale for Its Therapeutic Potential in Polycystic Ovary Syndrome.

Szukiewicz D·International journal of molecular sciences

Berberine (Liposomal)Aug 2026PubMed
Non-Pharmacological Strategies in Atherosclerotic Cardiovascular Disease: From Molecular Mechanisms to Clinical Integration.

Kovyanova TI, Nerush MO, Karagodin VP et al.·Biomedicines