The authority database
for longevity science
Peer-reviewed profiles, protocol stacks, and interaction data for peptides, nootropics, and longevity compounds — Oxford-graded, compliance-first.
96
Substances
34
Curated protocols
125
Research articles
4
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Featured Compounds
All 96 substances →Ashwagandha (KSM-66)
The most clinically studied adaptogen. KSM-66 is the highest-concentration ashwagandha root extract, backed by 12+ RCTs demonstrating significant cortisol reduction, testosterone support, and sleep quality improvement.
Astaxanthin
A red carotenoid from Haematococcus pluvialis — in 2023 became the first agent in the NIH ITP's 20-year history to exceed 10% lifespan extension in genetically heterogeneous mice (12% median male lifespan, Harrison et al. GeroScience 2024). Crosses the blood-brain and blood-retina barriers. Mechanism: Nrf2 activation, not direct scavenging.
Berberine (Liposomal)
An isoquinoline alkaloid that activates AMPK - the same pathway as metformin. Liposomal delivery overcomes berberine's poor bioavailability, making it one of the most powerful natural interventions for glucose management, lipid control, and metabolic longevity. Often called 'nature's metformin'.
BPC-157 (Body Protection Compound)
A pentadecapeptide derived from human gastric juice with remarkable tissue-healing properties. Acts locally and systemically to repair tendons, ligaments, muscles, and the gastrointestinal tract.
Cerebrolysin
A purified porcine brain-derived neuropeptide mixture containing low-molecular-weight peptides that mimic endogenous neurotrophic factors including BDNF, NGF, and CNTF. The most studied neuropeptide complex with over 30 years of clinical use for stroke, traumatic brain injury, and age-related cognitive decline.
Coenzyme Q10 (Ubiquinol)
Essential component of the mitochondrial electron transport chain required for ATP production in every cell. The Q-SYMBIO trial (420 patients, 2 years) showed 43% reduction in major cardiovascular events and 50% reduction in all-cause mortality with 300mg/day. The 2024 meta-analysis of 11,372 patients confirmed 5.6% absolute ejection fraction improvement. Critical for the ~200 million people on statin therapy worldwide.
FDA-compliant
All substance pages include mandatory FDA research disclaimers
EMA-compliant
EC Regulation 1924/2006 language on every EU-visible page
Peer-reviewed
Every compound reviewed by a credentialed researcher before publication
Recent Research
All articles →Estrogen Metabolism: DIM and Calcium-D-Glucarate Explained
Aug 25, 2026
The Menopause Transition Protocol: Building Non-Hormonal Support in Layers
Aug 25, 2026
Perimenopause Supplements: What the Evidence Actually Supports
Aug 24, 2026
The ApoB Optimization Protocol: Bergamot + Berberine + Omega-3
Aug 19, 2026
Nattokinase and Fibrinolysis: The Clot-Dissolving Enzyme
Aug 18, 2026
ApoB and Lp(a): The Cardiovascular Markers That Matter
Aug 17, 2026
The Inflammation Resolution Stack: Curcumin + Boswellia + SPMs
Aug 12, 2026
Specialized Pro-Resolving Mediators (SPMs): Beyond Omega-3
Aug 11, 2026