The authority database
for longevity science
Peer-reviewed profiles, protocol stacks, and interaction data for peptides, nootropics, and longevity compounds — Oxford-graded, compliance-first.
59
Substances
20
Curated protocols
77
Research articles
4
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Featured Compounds
All 59 substances →Ashwagandha (KSM-66)
The most clinically studied adaptogen. KSM-66 is the highest-concentration ashwagandha root extract, backed by 12+ RCTs demonstrating significant cortisol reduction, testosterone support, and sleep quality improvement.
Astaxanthin
A red carotenoid from Haematococcus pluvialis — in 2023 became the first agent in the NIH ITP's 20-year history to exceed 10% lifespan extension in genetically heterogeneous mice (12% median male lifespan, Harrison et al. GeroScience 2024). Crosses the blood-brain and blood-retina barriers. Mechanism: Nrf2 activation, not direct scavenging.
Berberine (Liposomal)
An isoquinoline alkaloid that activates AMPK - the same pathway as metformin. Liposomal delivery overcomes berberine's poor bioavailability, making it one of the most powerful natural interventions for glucose management, lipid control, and metabolic longevity. Often called 'nature's metformin'.
BPC-157 (Body Protection Compound)
A pentadecapeptide derived from human gastric juice with remarkable tissue-healing properties. Acts locally and systemically to repair tendons, ligaments, muscles, and the gastrointestinal tract.
Cerebrolysin
A purified porcine brain-derived neuropeptide mixture containing low-molecular-weight peptides that mimic endogenous neurotrophic factors including BDNF, NGF, and CNTF. The most studied neuropeptide complex with over 30 years of clinical use for stroke, traumatic brain injury, and age-related cognitive decline.
Coenzyme Q10 (Ubiquinol)
Essential component of the mitochondrial electron transport chain required for ATP production in every cell. The Q-SYMBIO trial (420 patients, 2 years) showed 43% reduction in major cardiovascular events and 50% reduction in all-cause mortality with 300mg/day. The 2024 meta-analysis of 11,372 patients confirmed 5.6% absolute ejection fraction improvement. Critical for the ~200 million people on statin therapy worldwide.
FDA-compliant
All substance pages include mandatory FDA research disclaimers
EMA-compliant
EC Regulation 1924/2006 language on every EU-visible page
Peer-reviewed
Every compound reviewed by a credentialed researcher before publication
Recent Research
All articles →The Senolytic Stack 2026: Quercetin + Fisetin + SGLT2 Combined Protocol
May 15, 2026
Epigenetic Reprogramming 2026: The First FDA-Cleared Human Trial of Cellular Age Reversal
May 13, 2026
Tesofensine vs Tirzepatide: The Triple Monoamine vs Dual Incretin Approach to Weight Loss 2026
May 11, 2026
Akkermansia muciniphila: The Next-Generation Probiotic for Metabolic Health
May 8, 2026
Urolithin A and the Immune System: The 2025 MitoImmune Trial Results
May 6, 2026
SGLT2 Inhibitors: The First Drugs That Reverse Telomere Aging in Humans
May 4, 2026
Cardiovascular Longevity Protocol: CoQ10 + Omega-3 + Astaxanthin Stack
May 1, 2026
The 2024 Q-SYMBIO Follow-Up: 10 Years of CoQ10 Cardiovascular Data
Apr 29, 2026