Research Blog
98 evidence-graded articles. Reviews, protocol guides, and study breakdowns — every piece is Oxford-scale rated and PubMed referenced.
The Athletic Longevity Stack: Creatine + Beta-Alanine + Citrulline + Taurine
High-intensity effort is a relay across three energy systems. This stack assigns one compound to each phase — creatine fuels, beta-alanine buffers, citrulline delivers, taurine supports — using four amino-acid-class compounds with strong safety profiles and a longevity angle.
Citrulline Malate vs L-Citrulline: Pump and Performance Science
Two forms, one confusing label. Citrulline malate and pure L-citrulline are dosed differently, studied differently, and bought differently — and most pre-workouts under-dose both. Here's how to read the label and pick the right form for your goal.
Beta-Alanine: The Endurance Supplement With the Most Evidence
Beta-alanine doesn't give you energy — it buys you time before your muscles acidify. By raising carnosine 40-80%, it delays the burn in 1-4 minute efforts. Here's the mechanism, the meta-analytic evidence, the right dose, and why it makes you tingle.
The Anti-Aging Skin Protocol: Collagen + Astaxanthin + GHK-Cu + Hyaluronic Acid
Skin ageing isn't one process — it's four. Matrix loss, oxidative breakdown, dehydration, and stalled remodelling. This protocol layers four evidence-backed compounds, each targeting a different mechanism, into a build-protect-hydrate-remodel stack.
Collagen Peptides Worth Taking: The 2026 Evidence Review
Most beauty supplements have nothing behind them. Collagen peptides are the rare exception — with real randomised trials for skin elasticity, hydration, and wrinkle depth. But the form, dose, and specific peptide fraction decide whether you get results or expensive protein powder.
Tributyrin vs Sodium Butyrate: Why The Form Matters
Same active molecule, completely different delivery. Sodium butyrate is mostly absorbed before it reaches the distal colon — where colonocytes actually need it. Tributyrin, a triglyceride prodrug, survives the stomach and releases butyrate where it counts.
Female Hormonal Optimization: DHEA + Pregnenolone + Maca Protocol
Female hormonal health gets treated as one switch — estrogen — when it's really a cascade. This protocol works that cascade from the top down: pregnenolone and DHEA restore the precursors, maca handles libido and energy, and bloodwork keeps it all in range.
Pregnenolone: The Mother Hormone for Brain and Stress
Every steroid hormone you make — cortisol, DHEA, testosterone, estrogen — begins as this one molecule. But pregnenolone isn't just a precursor sitting at the top of the cascade. It's a neurosteroid that tunes the two receptors most responsible for memory and calm.
DHEA at 50+: The Complete Hormonal Restoration Protocol
By 70, your body makes barely a fifth of the DHEA it did at 25 — the steepest hormonal decline you'll experience. Here's what restoring it actually does, what the evidence supports versus what's hype, and how to dose it without the androgenic side effects.
The Executive Cognitive Stack: Methylene Blue + Phosphatidylserine + Lion's Mane
Three compounds targeting three distinct cognitive pathways — mitochondrial energy, membrane function, and neurogenesis. A daily protocol with dosing, timing, and 12-month tracking plan.
Phosphatidylserine: The Forgotten Nootropic With Strong Stress Evidence
The only nootropic with an FDA-qualified health claim for cognitive decline. Multiple RCTs show 15-30% cortisol blunting during stress — yet somehow it's been overlooked for a decade.
Methylene Blue: From Aquariums to Biohacker Cognition
The oldest synthetic drug in medicine — patented in 1876 as a textile dye — turns out to be a mitochondrial electron carrier that boosts brain ATP production by up to 30% at micro-doses.