Research Blog
71 evidence-graded articles. Reviews, protocol guides, and study breakdowns — every piece is Oxford-scale rated and PubMed referenced.
Cardiovascular Longevity Protocol: CoQ10 + Omega-3 + Astaxanthin Stack
Cardiovascular disease is the leading cause of death globally — and the leading driver of accelerated aging. This protocol combines four supplements with strong RCT evidence into a coherent, evidence-tiered stack.
The 2024 Q-SYMBIO Follow-Up: 10 Years of CoQ10 Cardiovascular Data
When Q-SYMBIO was published in 2014, it should have changed cardiovascular medicine. A decade later, the follow-up evidence is even stronger — yet CoQ10 remains absent from heart failure guidelines. Here's what the data actually shows.
NMN vs NR: Which NAD+ Precursor Actually Works in 2026?
NMN and NR are the two most popular NAD+ precursors — but they're not interchangeable. Clinical evidence, FDA status, and cost all favour different precursors for different goals. Here's the data-driven breakdown.
Astaxanthin: The First Natural Supplement With 10%+ Lifespan Extension Evidence
The ITP tested dozens of compounds over 20 years. Only Rapamycin previously exceeded 10% lifespan extension — and it comes with immunosuppression. In 2023, Astaxanthin joined that elite group with a 12% result and zero safety concerns.
CoQ10 and Statins: Why Every Statin User Should Be Supplementing
200 million people take statins. The drug blocks the same enzyme needed to produce CoQ10 — depleting levels 40-50% within weeks. The Q-SYMBIO trial showed 43% reduction in cardiovascular events. The evidence for co-supplementation is overwhelming.
Quercetin and the Senolytic Revolution: The D+Q Protocol Explained
Quercetin isn't just an anti-inflammatory flavonoid. Paired with Dasatinib in the Mayo Clinic's D+Q protocol, it's the active partner in the only senolytic regimen with published human clinical trials. Pulsed dosing, bioavailability, and what the 2025 Alzheimer's data showed.
Urolithin A + SS-31: The Mitochondrial Synergy Stack for Cellular Energy Restoration
Urolithin A clears damaged mitochondria through mitophagy. SS-31 repairs the inner mitochondrial membrane and restores ATP production in existing mitochondria. Together they address mitochondrial ageing from two complementary angles — clearing the damaged and repairing the repairable.
Urolithin A: The Mitophagy Compound With Phase 2 Clinical Trial Data (2026)
Urolithin A is the only supplement-grade compound with Phase 2 clinical trial data demonstrating mitophagy induction in human muscle. It improves muscle endurance in older adults, reduces inflammation, and extends lifespan in multiple model organisms.
Turkesterone vs Ecdysterone: Which Ecdysteroid Wins for Muscle Growth? (2026)
Turkesterone and ecdysterone are the two most studied ecdysteroids for anabolic effects. A head-to-head comparison of mechanism differences, human RCT data, bioavailability challenges, optimal dosing, and which compound suits different goals — no hype, just evidence.
Turkesterone: The Ecdysteroid That Builds Muscle Without Affecting Hormones (2026)
Turkesterone is the most potent natural ecdysteroid, promoting muscle protein synthesis through non-androgenic pathways. No testosterone suppression, no virilisation, no post-cycle therapy.
Taurine + NMN Longevity Stack: The Anti-Aging Combination Backed by Science (2026)
Taurine and NMN target different but complementary ageing pathways — taurine via mitochondrial protection, telomere maintenance, and stem cell activation; NMN via NAD+ restoration.
Taurine for Longevity: What the 2023 Science Study Revealed
A June 2023 Science paper demonstrated taurine deficiency drives ageing across species — and supplementation extended mouse lifespan by 10-12% while reversing multiple hallmarks of ageing.