Research Blog
45 evidence-graded articles. Reviews, protocol guides, and study breakdowns — every piece is Oxford-scale rated and PubMed referenced.
Tongkat Ali and Fadogia Agrestis: The Evidence-Based Guide to Natural TRT Support
Tongkat Ali and Fadogia Agrestis are the most discussed natural testosterone support compounds. Tongkat Ali has genuine human RCT evidence for free testosterone elevation. Fadogia Agrestis has compelling rodent data but no human trials. We separate the evidence from the podcast hype.
The Wolverine Stack: Complete BPC-157 + TB-500 Guide for Athletes
The Wolverine Stack combines BPC-157's targeted local tissue repair with TB-500's systemic cell mobilisation. This guide covers the complete science, athlete-specific protocols by sport and injury type, timing optimisation, and how to cycle the stack for sustained recovery capacity.
Tesofensine 101: Why It Could Replace Ozempic in Biohacking in 2026
Tesofensine is a triple monoamine reuptake inhibitor that produced 10.6% body weight loss in 24 weeks in Phase 2 trials. With Phase 3 trials underway in 2026 and growing interest as a GLP-1 alternative, this is the weight loss compound most biohackers have never heard of.
Thymalin Protocol: Immune System Reset for Longevity
Thymalin is a thymus-derived peptide that reverses thymic involution — the progressive shrinkage of the thymus driving immunosenescence. Used alongside Epithalon in Khavinson's protocols, it targets the immune system's master organ to restore T-cell production capacity.
Thymosin Alpha-1 vs. Thymalin: Choosing the Right Immune Modulator
Both Thymosin Alpha-1 and Thymalin are derived from the thymus, but they differ fundamentally in characterisation, evidence quality, and clinical use. This comparison covers mechanisms, evidence, practical protocols, and when to use each.
Spermidine & Rapamycin: Synergistic Autophagy Cycles Without Muscle Loss
Spermidine and rapamycin induce autophagy via completely independent pathways. Combined, they produce additive autophagic flux while preserving lean mass — solving rapamycin's anabolic concern. The evidence, the mechanism, and the practical protocol.
SS-31 (Elamipretide): Reversing Mitochondrial Aging at the Inner Membrane
SS-31 is the only compound that directly targets cardiolipin in the inner mitochondrial membrane, restoring cristae architecture and electron transport chain efficiency. Phase 2 clinical data in heart failure. The structural foundation of any serious mitochondrial restoration protocol.
TB-500 (Thymosin Beta-4): Angiogenesis and Muscle Recovery Science
TB-500 is a synthetic analogue of Thymosin Beta-4, present in virtually every human cell. Its primary mechanism — systemic actin polymerisation regulation — enables rapid mobilisation of repair cells throughout the body. This deep dive covers the angiogenesis science and why it pairs...
The Senolytic Protocol: Fisetin and Clearing Zombie Cells
Senescent cells accumulate with age and drive systemic inflammation via the SASP. This evidence-based guide covers fisetin's senolytic mechanism, the pulsed dosing rationale, and how to build an effective senolytic protocol.
The Science of Telomeres 2026: How to Measure and Why It Matters
Telomeres are now measurable via consumer blood tests. By 2026, telomere length has become a trackable biological age biomarker. This guide covers the science, testing options, what the numbers mean, and which interventions have real evidence for elongation.
Semax & Selank: The Gold Standard of Nasal Nootropics
Semax and Selank are synthetic peptides approved as prescription medications in Russia and used as the most effective nasal nootropic combination available. Semax drives cognitive performance via BDNF; Selank provides anxiolysis without sedation. Together they produce a balanced flow state.
Safety and Biohacking Ethics: How to Read a COA and Not Buy Chalk
The research peptide market has no regulatory oversight. This guide covers exactly how to verify what you are buying, which tests matter, how to read a COA, and the ethical framework for intelligent self-experimentation with research compounds.