The authority database for longevity science
BiohackingHub is an independent research portal dedicated to evidence-based longevity science. We exist because the internet is full of supplement hype, undisclosed affiliate marketing, and cherry-picked studies. We are trying to be the opposite of that.
Our goal: a single reference where a practitioner, researcher, or informed individual can find the most accurate, current, and safety-conscious information on longevity compounds — without needing to parse primary literature themselves.
41
Substances reviewed
14
Curated protocols
45
Research articles
6
Expert reviewers
What we stand for
These principles guide every editorial decision we make.
Evidence first
Every claim is backed by PubMed-indexed citations. We grade all content using the Oxford Centre for Evidence-Based Medicine scale — so you always know the strength of the evidence behind a claim.
Radical transparency
Affiliate relationships, reviewer credentials, and evidence limitations are disclosed prominently — not buried in footnotes. If evidence is weak, we say so explicitly.
Safety above engagement
We do not sensationalise compounds to drive traffic. Tier ratings, contraindications, and drug interactions are always presented before benefits. Prescription drugs are clearly labelled as such.
Living database
The science of longevity evolves rapidly. We update profiles, add new research, and revise claims when better evidence emerges. Every page shows its last-reviewed date.
How content is created and reviewed
Every substance profile, protocol, and article follows the same six-step process.
Primary research
Our Research Team conducts systematic literature review across PubMed, examining clinical trials, meta-analyses, and mechanistic studies.
Evidence grading
Every claim is graded on the Oxford CEBM scale (1a–5). Each substance receives an overall Evidence Grade (A–D) and Safety Tier (A–D).
Expert review
Content passes to the specialist reviewer for that topic area — metabolic, neurological, gut health, longevity, or general. Reviewers check accuracy, flag missing context, and ensure safety information is complete.
Compliance check
Legal review ensures FDA (US) and EC 1924/2006 (EU) compliant language on all substance profiles. Prescription drugs are clearly identified.
Publication
Published with author, reviewer, and date visible. PubMed references listed at the bottom of every article.
Ongoing updates
Profiles are re-reviewed when significant new evidence is published. The 'last reviewed' date is updated with each revision.
Expert review team
All substance profiles and research articles are reviewed by credentialed specialists in the relevant field. Reviewers operate independently of commercial relationships.
Dr. Aleksei Volkov, MD, PhD
Longevity & Peptide Therapy Reviewer
Peptide bioregulators and Khavinson protocols · Telomere biology and epigenetic ageing
Dr. Jane Smith, MD, PhD
Chief Medical Reviewer
Longevity medicine & biological age reversal · Peptide therapeutics and regulatory pharmacology
Dr. Michael Chen, MD
Metabolic Medicine Reviewer
GLP-1 receptor agonists and incretin therapy · Metabolic syndrome and insulin resistance
Dr. Priya Nair, MD, MSc
Gastroenterology & Gut Health Reviewer
Intestinal barrier function and tight junction biology · Inflammatory bowel disease and mucosal immunology
Dr. Sarah Okonkwo, PhD
Neuroscience & Peptide Reviewer
Peptide nootropics and synaptic plasticity · BDNF, NGF, and neurotrophic factor biology
BiohackingHub Research Team
Editorial Research Team
Systematic literature review and evidence grading · Peptide pharmacology and bioavailability research
Independence & compliance
Editorial independence
Affiliate relationships never influence editorial ratings, safety tiers, or evidence grades. Reviewers are not compensated by supplement brands. Sponsored content is clearly labelled and does not appear within substance profiles.
Regulatory compliance
All substance profiles include FDA-compliant research disclaimers (US) and EC Regulation 1924/2006 compliant language (EU). Prescription medications are identified as such. Research peptides are labelled for research purposes only.
Data privacy
The Protocol Journal and Biomarker Tracker store all data locally in your browser — nothing is sent to our servers. We comply with GDPR and CCPA. Cookie consent is required before any non-essential tracking.
Get in touch
Found an error? Have a correction? Want to submit a COA or contribute research? We take accuracy seriously and respond to all substantive feedback.